Liquid D and K, provided by Douglas Laboratories is a unique, great tasting liquid supplying significant amounts of vitamins K1 and K2 as well as vitamin D3 to support optimal bone health.

FUNCTIONS

Vitamin K

A growing body of literature supports the concept that increased intake of vitamin K both from food as well as supplements can have a beneficial impact on bone health. While the term “vitamin K” may imply a single molecule, vitamin K is actually a group of similar molecular forms including K1 (phylloquinone) and K2 (menaquinone). Liquid D and K has been specially formulated to include the most important molecular forms of vitamin K for optimal health.

Vitamin K1 is the most abundant form of vitamin K in the diet and is most often found in green vegetables such as spinach, lettuce and broccoli. Often this source of vitamin K is difficult to obtain in sufficient amounts from the diet, as the molecule can be bound tightly to the chloroplast membrane in the plant. Vitamin K1 is well regarded for the important roles it plays in the body’s normal blood clotting mechanisms

Vitamin K2 is not commonly found in the diet; as only a few products including meats and certain fermented foods provide this relatively rare form of the vitamin. Vitamin K2 is actually comprised of a group of several different molecules, abbreviated as MK-n, where n represents a number. MK-4, found in some animal meats and liver, and MK-7, found in fermented cheeses and soy products (Natto) are two of the most studied forms of vitamin K2. Supplementation with this vitamin is important as most people do not receive enough vitamin K2 from diet alone.

Human studies show that vitamin K plays important roles in bone health. Vitamin K has been shown to decrease calcium excretion and is involved in gamma-carboxylation of osteocalcin. Osteocalcin is important for healthy bone formation, as it facilitates the binding of calcium to hydroxyapatite (bone matrix). Additional studies also indicate the vitamin K2 may play important roles in supporting cardiovascular health and normal arterial elasticity.

While Vitamin K1 has shown to be useful in some studies, vitamin K2 is thought to have additional, beneficial effects, as the body has a natural preference to accumulate this vitamin in tissues such as bone. MK-7, a natural form of vitamin K2, in particular has shown to have rapid bioavailability in the body and the low dosages required (45 mcg) can be effective for supporting bone health.

Vitamin D3

Vitamin D is well known for the role it plays in helping to regulate calcium and bone metabolism. As we age, vitamin D status declines. If given the same amount of light, a younger person can produce more vitamin D compared with an older individual. When advancing age is combined with northern latitudes one can quickly become deficient in vitamin D. Vitamin D can increase the expression of osteocalcin and other important compounds from osteoblasts to help support bone formation or it can help to breakdown bone and mobilize calcium when it is needed elsewhere in the body. Numerous scientists now feel that supplementation with vitamin D at levels greater than previously thought necessary is critical to helping maintain healthy bone remodeling as we age.

• There is widespread emerging concern about the frequency of low vitamin D status in the North American population (Am Fam Physician 2005;71:241-2).
• Vitamin D is the precursor of 1,25 dihydroxycholecalciferol, an extremely potent hormone that promotes the intestinal absorption of calcium.
• Vitamin D supplementation can augment the favorable effect of calcium supplementation on bone health in postmenopausal women (Am J Clin Nut 1995;61:1140-45).
• Optimal results from medical treatments for supporting adequate bone density requires a total vitamin D intake of 600 IU/day (J Am Coll Nutr 2000;19:83S-99S).
• Recent research has identified a role for vitamin D in supporting optimal neuromuscular function to stabilize balance and gait in elderly persons; total vitamin D intake must be above 400 IU for maximum effectiveness (Arch Intern Med 2006;166:424-30; J Am Geriatr Soc 2005;53:1881-8; Cerebrovasc Dis 2005;20:187-92; JAMA 2004;291:1999-2006).
• A recent meta-analysis of twelve trials concluded that vitamin D supplements totaling at least 700 IU/day help bones maintain their integrity during minor traumas (JAMA 2005;293:2257-64).
• Natural vitamin D3 is more bioavailable than synthetic vitamin D2 (Am J Clin Nutr 1998;68:854-8; Bone Miner 1986;1:407-413).

HydroxyCal supplies an efficient complex of nutrients and cofactors that support bone strength and maintenance. Calcium is supplied as citrate as well as in a freeze-dried, whole-bone bovine extract. This extract is also a rich source of bone matrix proteoglycans and trace minerals, and has been shown to be exceptional for supporting bone maintenance and repair. A generous amount of vitamin K is included, far more than in most other bone support products, and vitamin D is supplied in the preferred D3 form for maximum bioavailability. These nutrients, along with vitamin C and manganese, work together to support optimal bone density and help skeletal structures maintain their integrity during minor traumas.

• Whole bone bovine extract is a rich source of calcium, trace minerals and structural support molecules, which are effectively preserved by freeze-drying.
• HydroxyCal contains microcrystalline hydroxyapatite complex from whole bone, which has been shown to support bone remineralization (Am J Clin Nutr 1982;36:426-30) and optimum skeletal repair processes (Manitoba Med Rev 1965;45:92-6).

Cal : Mag Berry Liquid + 15.2 fl oz

Vitamin-Mineral Supplement

• Natural Blueberry Flavor
• 100% Citrate Minerals with Vitamins A, D, K and Boron

Supplement Facts
Serving Size: 1 Tablespoon (15 ml)
Servings per Container: 30

Amount Per Serving
Vitamin A 1000 IU
(vitamin A acetate)
Vitamin C 9 mg
Vitamin D (cholecalciferol) 1000 IU
Vitamin K1 (phylloquinone) 80 mcg
Vitamin K2 (menaquinone-7)t 20 mcg
Calcium (calcium citrate) 500 mg
Magnesium 200 mg
(magnesium citrate)
Boron (boron citrate) 2000 mcg
Stevia (Stevia rebaudiana) 3.4 mg
leaf std. extract (95% glucosylsteviosides)

Other ingredients: Purified water, xylitol, natural blueberry flavor, xanthan gum, citric acid, potassium sorbate, ascorbic acid

Recommended adult intake: One tablespoon taken once daily with a meal, a few hours before or after taking other medications, or as professionally directed.

Risk information: If you are pregnant or breastfeeding, do not use. If you are taking blood thinners, or if you have been diagnosed with estrogen-dependent cancer, consult your healthcare practitioner prior to use.

Safety-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken. Shake well before each use. Store in a cool, dry place.

Keep out of reach of children.